Figure 1
From: Sympathetic modulation of hindlimb muscle contractility is altered in aged rats
Effect of lumbar sympathetic trunk (LST) transection on the tetanic force (TF) of the triceps surae muscles. (A) Example responses in each young and aged rat of the TF induced by tibial nerve stimulation before (LST intact) and 20 min after LST transection (LST cut). The traces show the superimposed contraction curves, each averaged over 30 contractions before (dotted line) and after (solid line) LST transection. (B) Graph summarizing the changes in the amplitude of the TF in the young adult (n = 11 rats) and aged (n = 11 rats) groups, expressed as the percent change of control TF before LST transection. **P < 0.01 (paired t-test, vs. control TF with intact LST). (C) Subgroup analysis of age and sex. (D) Correlation between muscle weight (% of body weight) and changes in TF (% of control force) induced by the LST cut was tested by simple linear regression. Each column, vertical bar, and circle indicates the median, interquartile range, and individual data, respectively.
