Table 1 White blood cell counts profiles between patients and matched healthy controls in AQP4-IgG-positive NMOSD and MOGAD.

From: White blood cell count profiles in anti-aquaporin-4 antibody seropositive neuromyelitis optica spectrum disorder and anti-myelin oligodendrocyte glycoprotein antibody-associated disease

 

Patients

1:5 matched controls

P-values

AQP4-IgG-positive NMOSD (Patient group: n = 13 vs matched controls: n = 65)

 Total WBC count

6700 (4810–7440)

5500 (4500–6100)

0.0723

 Hemoglobin [g/dL]

14.1 (13.6–14.5)

13.4 (12.7–14.2)

0.1955

 Platelet count [103/μL]

24.8 (21.4–31.2)

25.8 (22.3–29.0)

0.8986

 Neutrophil [/μL]

4520 (2880–5280)

3260 (2710–3720)

0.0247

 Eosinophil [/μL]

50 (20–80)

110 (50–170)

0.0111

 Basophil [/μL]

10 (10–30)

30 (20–40)

0.0283

 Lymphocyte [/μL]

1230 (1140–1720)

1690 (1350–2060)

0.0511

 Monocyte [/μL]

290 (250–380)

240 (180–300)

0.0359

 PLR

175.2 (138.5–198.3)

149.1 (125.8–190.0)

0.1315

 MLR

0.229 (0.157–0.248)

0.139 (0.110–0.162)

0.0004

 NLR

3.134 (1.835–4.485)

1.899 (1.438–2.381)

0.0037

MOGAD (Patient group: n = 26 vs matched controls: n = 130)

 Total WBC count

6350 (5550–7380)

5200 (4430–6350)

0.0001

 Hemoglobin [g/dL]

13.8 (12.6–14.8)

13.7 (12.8–14.6)

0.8753

 Platelet count [10^3/μL]

26.0 (22.9–31.6)

24.4 (21.0–28.1)

0.0578

 Neutrophil [/μL]

4040 (3230–5090)

2960 (2390–3700)

 < 0.0001

 Eosinophil [/μL]

90 (60–190)

110 (70–200)

0.5927

 Basophil [/μL]

30 (20–50)

30 (20–40)

0.3415

 Lymphocyte [/μL]

1860 (1600–2220)

1750 (1520–2140)

0.4965

 Monocyte [/μL]

320 (240–360)

250 (210–310)

0.0191

 PLR

150.5 (113.1–185.0)

134.9 (107.7–166.5)

0.1799

 MLR

0.164 (0.138–0.196)

0.146 (0.116–0.179)

0.0320

 NLR

2.169 (1.788–3.072)

1.692 (1.355–2.108)

0.0002

  1. Median and interquartile range (25–75 percentiles) for each variable are shown.
  2. AQP4 aquaporin-4, MOGAD anti-myelin oligodendrocyte glycoprotein antibody-associated disease, NMOSD neuromyelitis optica spectrum disorder.