Figure 2
From: A system that delivers an antioxidant to mitochondria for the treatment of drug-induced liver injury
Evaluation of physical properties of the MITO-Porter with or without PEG, R8 and CoQ10. The prepared LNPs were characterized by three indices: (A) particle size, (B) dispersibility, (C) ζ-potential. The results of the physical properties of (a) Empty-MITO-Porter and (b) CoQ10-MITO-Porter are compared to consider the effect of CoQ10, a poorly water-soluble molecule. Circles represent the values of 4 individual samples and bars are the mean (n = 4). Data represented the mean ± S.D. (n = 4). Significant differences were calculated by two-way ANOVA, followed by Tukey test (***p < 0.001). In supplementary information, Table S1 shows the physical properties of the MITO-Porters.
