Table 1 Two-way ANOVA analysis of the physicochemical property of the MITO-Porters.
From: A system that delivers an antioxidant to mitochondria for the treatment of drug-induced liver injury
Sample | Parameter | Factors | P-value by 2-way ANOVA | Significant difference |
|---|---|---|---|---|
Empty-MITO-Porter | Particle size | PEG | 4.6 × 10–10 | < 0.001 |
R8 | 5.1 × 10–10 | < 0.001 | ||
Interaction between two factors | 5.0 × 10–10 | < 0.001 | ||
Dispersibility | PEG | 2.8 × 10–1 | NS | |
R8 | 6.3 × 10–2 | NS | ||
Interaction between two factors | 5.3 × 10–4 | < 0.001 | ||
ζ-potential | PEG | 2.9 × 10–5 | < 0.001 | |
R8 | 1.1 × 10–11 | < 0.001 | ||
Interaction between two factors | 3.3 × 10–7 | < 0.001 | ||
CoQ10-MITO-Porter | Particle size | PEG | 5.5 × 10–8 | < 0.001 |
R8 | 1.5 × 10–7 | < 0.001 | ||
Interaction between two factors | 1.5 × 10–7 | < 0.001 | ||
Dispersibility | PEG | 1.9 × 10–6 | < 0.001 | |
R8 | 5.8 × 10–1 | NS | ||
Interaction between two factors | 4.9 × 10–1 | NS | ||
ζ-potential | PEG | 2.0 × 10–10 | < 0.001 | |
R8 | 4.2 × 10–16 | < 0.001 | ||
Interaction between two factors | 5.3 × 10–12 | < 0.001 |
