Figure 1

Mendelian randomisation study design. BBJ BioBank Japan, FC fasting C-peptide, FG fasting glucose, FI fasting insulin, HbA1c haemoglobin A1c, HERPACC the Hospital-based Epidemiologic Research Program at Aichi Cancer Centre, J-MICC the Japan Multi-Institutional Collaborative Cohort, JPHC Japan Public Health Center, TMM the Tohoku Medical Megabank, SNP single nucleotide polymorphism.