Table 3 Associations between clinicopathological findings and overall survival.

From: Histological markers, sickle-shaped blood vessels, myxoid area, and infiltrating growth pattern help stratify the prognosis of patients with myxofibrosarcoma/undifferentiated sarcoma

 

HR (95% CI)

P

 

HR (95% CI)

P

Gender (male, female)

0.838

0.757

Hemorrhage area (%)*

1.022

0.088

(0.273–2.573)

(0.997–1.048)

Age (years)

1.006

0.745

Fibrotic change (%)*

0.992

0.647

(0.970–1.043)

(0.959–1.026)

Local recurrence (positive, negative)

0.34

0.152

Pleomorphic component (%)*

1.008

0.291

(0.078–1.490)

(0.993–1.023)

Metastasis (positive, negative)

325.394

0.027

Epithelioid component (%)*

1.024

0.003

(1.909–55,470.380)

(1.008–1.040)

Tumor size (mm)

1.006

0.093

Inflammatory cells infiltration

0.629

0.384

(0.999–1.013)

(0.222–1.786)

Resection margin (positive, negative)

0.423

0.133

Histiocytes accumulation

1.426

0.578

(0.138–1.300)

(0.409–4.966)

Mitosis (10 HPF)*

1.027

0.008

Cystic change

0.929

0.699

(1.007–1.047)

(0.638–1.351)

Necrosis area (%)*

1.03

0.002

Rhabdoid cells component

3.046

0.022

(1.011–1.049)

(1.171–7.920)

Vascular invasion (positive, negative)

2.729

0.062

Giant cells component

0.376

0.055

0.952–7.821

(0.138–1.022)

Sickle-shaped blood vessels**

15.351

 < 0.001

FNCLCC (G1, G2, G3)

6.351

0.002

(5.585–42.2000)

(1.992–20.252)

Myxoid area (%)*

0.966

0.023

   

(0.938–0.995)

  1. Statistically significant P-values are shown in bold.
  2. *The HRs are for 1 mitosis or 1% increase.
  3. **For analysis of sickle-shaped blood vessels, we dichotomized the cases based on the number of vessels in the maximum cut-surface of each tumor into those with 1–99 vessels and those with ≥ 100 vessels.
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