Table 2 Characteristics of IL1B three htSNPs selected and SNPs in PPP1R13L and POLR1G.

From: Common variants of pro-inflammatory gene IL1B and interactions with PPP1R13L and POLR1G in relation to lung cancer among Northeast Chinese

Gene/chromosome/rsa

Position

Functional consequence

Base change

Allele frequency in HapMap HCBb

Control MAFc in this study

IL1B Chr2q14.1

 rs1143633

112832890

Intron

A/G

A0.5465/G0.4535

G0.46

 rs3136558

112833698

Intron

T/C

T0.7442/C0.2558

C0.38

 rs1143630

112834078

Intron

C/A

C0.9024/A0.0976

A0.16

PPP1R13L Chr19q13.32

 rs1970764

45387615

Intron

A/G

No

G0.48d

POLR1G Chr19q13.32

 rs967591

45406676

5′ UTR

G/A

G0.5250/A0.4750e

A0.42d

 rs735482

45408744

Exon, missense

A/C

A0.5581/C0.4419

C0.45d

  1. aInformation from NCBI SNP database (GRCh38.p12) and HapMap database. From 3′–5′.
  2. bHan Chinese in Beijing.
  3. cMinor allele frequency.
  4. dFrom previous result (Yin et al.18), here this is employed for interaction analysis.
  5. eCHB + JPT (Han Chinese in Beijing + Japanese from 1000GENOMES).
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