Figure 5 | Scientific Reports

Figure 5

From: Glucagon-like peptide-1 facilitates cerebellar parallel fiber glutamate release through PKA signaling in mice in vitro

Figure 5

GLP-1 increased the frequency of mEPSCs in cerebellar PCs. (A) In the presence of gabazine(20 μM) and TTX (1 μM), representative membrane current traces of a cerebellar PC recorded in control, GLP-1 (100 nM) and washout. (B) Cumulative probability-interevent interval curve of mEPSCs in control, GLP-1 and washout. (C) Cumulative probability-amplitude curve of mEPSCs in control, GLP-1 and washout. (D, E) The mean (± S.E.M) and individual data show the normalized mEPSCs frequency (D) and amplitude (C) of the PCs in control, GLP-1 and washout. n = 7 cells in each group. * P < 0.05 versus control, n = 7 cells in each group.

Back to article page