Table 3 Different classes of DILI and control group.
From: Increased TG to HDL-C ratio is associated with severity of drug-induced liver injury
DILI group | Control group | P | |
|---|---|---|---|
Classes of drugs | |||
Chinese herbal medicines N(%) | 112 (50.68) | 14 (5.69) | < 0.01 |
Western medicines N(%) | 75 (33.94) | 176 (71.54) | |
Both N(%) | 34 (15.38) | 56 (22.76) | |
Patterns of liver injury | |||
Hepatocellular N(%) | 94 (42.53) | – | |
Cholestatic N(%) | 104 (47.06) | ||
Mix N(%) | 23 (10.41) | ||
Severity of liver injury | |||
Level 1 N(%) | 103 (46.61) | – | |
Level 2 N(%) | 45 (20.36) | ||
Level 3 N(%) | 30 (13.57) | ||
Level 4 N(%) | 43 (19.46) | ||
Duration of medication | |||
≤ 31 days N(%) | 177 (80.09) | – | |
32–365 days N(%) | 34 (15.38) | ||
> 1 year N(%) | 10 (4.52) | ||
Indication of drugs | |||
Cardiovascular drugs N(%) | 8 (3.62) | 77 (31.3) | < 0.01 |
Psychiatry drugs N(%) | 11 (4.98) | 10 (4.07) | |
Analgesic and antipyretic drugs N(%) | 46 (20.81) | 72 (29.27) | |
Antineoplastic drugs N(%) | 26 (11.76) | 6 (2.44) | |
Digestive system drugs N(%) | 7 (3.17) | 5 (2.03) | |
Obstetric/gynecological drugs N(%) | 2 (0.9) | 1 (0.41) | |
Rheumatism drugs N(%) | 2 (0.9) | 60 (24.39) | |
Endocrine drugs N(%) | 7 (3.17) | 27 (10.98) | |
Urinary system drugs N(%) | 6 (2.71) | 3 (1.22) | |
Healthy care drugs N(%) | 83 (37.56) | 32 (13.01) | |
Anti-inflammatory drugs N(%) | 18 (8.14) | 9 (3.66) | |
Others N(%) | 21 (9.5) | 12 (4.88) | |
