Figure 4
From: An injectable copolymer of fatty acids (ARA 3000 BETA) as a promising treatment for osteoarthritis
ARA 3000 BETA protected knee joint soft tissues from OA-associated calcification. (A) Representative 3D reconstructed images of knee joints in healthy (H) mice and CIOA mice not treated (OA) or treated with four intra-muscular (IM) injections or one (IA1) or two intra-articular (IA2) injections of ARA 3000 BETA (Ara) after micro-CT analysis showing mineralized menisci and external ligaments. (B) Histomorphometric analysis of bone volume (BV) and surface (BS) of mineralized tissues in knee joints. Results are expressed as the mean ± SEM; *p < 0.05; ***p < 0.001 (ANOVA test with Dunn’s post-test as compared to OA control; n = 15 mice).
