Figure 3

Hidden Markov modelling reveals differences in tail addition enzyme activities between total RNA and circRNA of the same transcript. Percentage of adenine addition (red) and uridine addition (blue) are shown for each state by proportion of the circle colored. The percentage of tails that move from one state to another is shown by thickness of arrows. Actual percentages are written next to arrows of particular interest. Grey, starting state; 1, primarily A-adding state; 2, primarily U-adding state; 3, A/U-adding state.