Figure 6

Photodynamic therapy (PDT) efficacy. Non-biological efficacy of (A) DPBF (50 μM in DMSO) absorbance decay (%) for the 1O2 photogeneration efficacy of MPPa with/without SLNs at 418 nm after photoirradiation (total light dose 2 J/cm2; irradiation time 15 min). Statistical significance of the difference in DPBF between MPPa solution and the formulations is indicated by either a single asterisk (p < 0.05) or double asterisks (p < 0.01). Biological efficacy for (B) HeLa cell line and (C) A549 cell line treated with MPPa solution, F1, F3, F7, and F9. The cell viability was measured using the WST assay. Results are expressed as means ± standard deviations of three independent experiments (n = 3).