Table 4 Multivariable adjusted* linear regression of MMSE/MoCA scores with SUA within subgroups.

From: The association between serum uric acid and cognitive performance in patients with ischemic stroke is modified by estimated glomerular filtration rate

Subgroups

MMSE

P for interaction

MoCA

P for interaction

Q1-Q3

Q4

Q1-Q3

Q4

ß (95%CI) P

ß (95%CI) P

Gender

0.292

  

0.485

Male

0

0.06 (-0.38, 0.51)0.779

 

0

0.21 (-0.25, 0.66) 0.370

 

Female

0

0.48 (-0.22, 1.19) 0.181

 

0

0.50 (-0.25, 1.25) 0.195

 

Age dichotomous

0.160

  

0.594

Lower

0

-0.07 (-0.61, 0.48) 0.813

 

0

0.14 (-0.46, 0.74) 0.642

 

Higher

0

0.45 (-0.08, 0.98) 0.099

 

0

0.35 (-0.18, 0.87) 0.198

 

Systolic blood pressrue dichotomous

0.779

  

0.880

Lower

0

0.11 (-0.43, 0.66)0.682

 

0

0.20 (-0.36, 0.77) 0.481

 

Higher

0

0.22 (-0.32, 0.75) 0.424

 

0

0.26 (-0.29, 0.82) 0.355

 

NIHSS score dichtomous

 

0.867

  

0.393

Lower

0

0.13 (-0.44, 0.71)0.647

 

0

0.04 (-0.56, 0.63) 0.906

 

Higher

0

0.07 (-0.43, 0.57) 0.778

 

0

0.37 (-0.15, 0.89) 0.168

 

Stroke subtypes

 

0.548

  

0.997

Large artery

0

0.11 (-0.47, 0.68) 0.721

 

0

0.27 (-0.32, 0.86) 0.372

 

Small vessel occlusion

0

0.33 (-0.17, 0.83) 0.202

 

0

0.27 (-0.27, 0.81) 0.331

 

eGFR dichotomous

 

0.016

  

0.005

Lower

0

-0.65 (-1.20, -0.11) 0.020

 

0

-0.90 (-1.50, -0.29) 0.004

 

Higher

0

0.02 (-0.60, 0.64) 0.946

 

0

0.12 (-0.55, 0.80) 0.724

 

Blood glucose dichotomous

0.695

  

0.981

Lower

0

0.27 (-0.23, 0.76) 0.298

 

0

0.36 (-0.18, 0.89) 0.193

 

Higher

0

0.10 (-0.46, 0.67) 0.718

 

0

0.25 (-0.32, 0.82) 0.391

 
  1. SUA serum uric acid, ß standardized regression coefficient, CI confidence interval, eGFR estimated glomerular filtration rate, UACR urine albumin creatinine ratio, NIHSS National Institutes of Health Stroke Scale.
  2. *Adjusted, if not stratified, age, gender, BMI, systolic blood pressure, education, diabetes and hypertension history, stroke subtypes, NIHSS scores, smoking and alcohol drinking status, serum total cholesterol, triglyceride, vitamin B12, folate, fasting glucose, UACR and eGFR.