Figure 4
From: Exploring the mechanism underlying hyperuricemia using comprehensive research on multi-omics

Mendelian randomization analysis of the association between caffeine-containing drinks and gout risk. Coffee and tea were analyzed respectively. None-caffeine herbal tea was used as a negative control. (A) Directed acyclic diagram demonstrating the core assumptions of Mendelian randomization in this study. (B) SNP effects on the outcome are plotted against SNP effects on the exposure. (C) Funnel plot to assess heterogeneity. (D) Mendelian randomization analysis results. MRBASE (1.4.3 8a77eb) was used to conducted the analysis and plotting.