Figure 4 | Scientific Reports

Figure 4

From: In vitro and in vivo susceptibility to sulfadiazine and pyrimethamine of Toxoplasma gondii strains isolated from Brazilian free wild birds

Figure 4The alternative text for this image may have been generated using AI.

Survival and brain cyst analysis of Swiss mice infected with Wild 2, Wild 3, and Wild 4 after treatment with SDZ, PYR, and their combination for 10 days. (A,C,E) Swiss mice (n = 10 per group) were intraperitoneally infected with 104 tachyzoites of Wild 2 (A), Wild 3 (C), and Wild 4 (E) strains. The oral treatment was initiated on day 2 after infection (black arrows) and lasted for 10 days (day 12; red arrows). Mice survival was followed until day 30. (B,D,F) Brain cyst number quantification in surviving mice after 30 days. #P < 0.05 compared to SDZ + PYR (One Way ANOVA and Bonferroni post-test). *No mice survived at those doses.

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