Table 1 Median of survival and percent of survived mice after the treatments for 10 and 17 days.
Treatment groups | 10-days of treatment | 17-days of treatment | ||
|---|---|---|---|---|
Median of survival (days) | % of survived mice on day 30 DPI | Median of survival (days) | % of survived mice on day 37 DPI | |
Wild 2 | ||||
Untreated | 8 | 0 | 10 | 0 |
SDZ10 | 18 | 0 | 9 | 0 |
SDZ40 | 21 | 0 | 25 | 0 |
SDZ160 | 22 | 10 | > 37 | 85,7 |
PYR3 | 25 | 40 | 10 | 0 |
PYR12 | 24,5 | 20 | 28 | 14,3 |
PYR50 | 27 | 30 | > 37 | 100 |
SDZ + PYR | 29,5 | 40 | > 37 | 100 |
Wild 3 | ||||
Untreated | 12,5 | 0 | – | – |
SDZ10 | 26,5 | 50 | – | – |
SDZ40 | > 30 | 100 | – | – |
SDZ160 | > 30 | 90 | – | – |
PYR3 | > 30 | 60 | – | – |
PYR12 | > 30 | 100 | – | – |
PYR50 | > 30 | 100 | – | – |
SDZ + PYR | > 30 | 100 | – | – |
Wild 4 | ||||
Untreated | 7 | 0 | 12 | 0 |
SDZ10 | 15,5 | 0 | 15 | 0 |
SDZ40 | 20,5 | 10 | 22 | 0 |
SDZ160 | 27 | 50 | > 37 | 85,7 |
PYR3 | 13 | 0 | 24 | 14,3 |
PYR12 | > 30 | 80 | > 37 | 57,1 |
PYR50 | > 30 | 100 | > 37 | 100 |
SDZ + PYR | > 30 | 70 | > 37 | 100 |