Table 1 Summary of genomic alteration of F0 mice induced by genome editing.

Genomic alteration	Sequence							Male	Female	Total
Genomic alteration	CCA	AGT	CGA	GTG	TCC	TTC	CT	Male	Female	Total
C-to-T conversion	CtA	AGT	CGA	GTG	TCC	TTC	CT	5	3	8
A T-insertion	CCA	AGTtCGA		GTG	TCC	TTC	CT	1	2	3
A G-insertion	CCA	AGTgCGA		GTG	TCC	TTC	CT	1	0	1
5-Nucleotide deletion	CCA	– – – – – – A	GTG	GTG	TCC	TTC	CT	0	2	2
Small deletion^a and others	N/A							2	4	6
Sum								9	11	20

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