Figure 6 | Scientific Reports

Figure 6

From: Identification of three elevenin receptors and roles of elevenin disulfide bond and residues in receptor activation in Aplysia californica

Figure 6

Bioinformatics of putative elevenin receptors. (A) Prediction of seven transmembrane domains of putative receptors: apElevR1, apElevR2, apElevR3 using TMHMM 2.0 (https://dtu.biolib.com/DeepTMHMM). Conserved motifs in transmembrane domain 3 (TM3, D/ERY) and TM7 (NPXXY) are shown. The last residue, N, of TM3 motif for apElevR3 is shown in red because it is not conserved. (B) A phylogenetic tree of the three Aplysia proteins, apElevR1, apElevR2, apElevR3 (shown in orange), and two putative elevenin receptors (marked by *) of L. gigantea and C. gigas with a number of Class A GPCR sequences derived from our previous work8. The tree is drawn to scale, with branch lengths measured in the number of substitutions per site. Numbers at the nodes are bootstrap values as a percentage. Only bootstrap values greater than 50 are shown.

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