Figure 1

Induction of hydrogen peroxide-inducible clone-5 (Hic-5) expression in human osteoarthritis (OA) cartilage. (A,B) Representative immunohistochemical staining of Hic-5 in normal and OA cartilage. Broken lines indicate the articular cartilage surface. Original magnification × 100 in (A); × 400 in (B). Bar = 100 μm. (C) Quantification of Hic-5-positive cells in normal (n = 3) and OA cartilage (n = 3). Data were analyzed by the unpaired t test. Values are the mean ± SEM. **P < 0.01.