Table 1 Demographic and clinical data in HAM/TSP and AC Brazilian patients.
HAM/TSP (n = 210) | AC (n = 165) | OR (95% CI)/mean ± SD | P-value | |
|---|---|---|---|---|
Sex (n, %) | ||||
Female | 132 (62.9) | 90 (54.5) | – | – |
Male | 78 (37.1) | 75 (45.5) | 0.71 (0.47–1.07) | 0.1 |
Age (years) | ||||
Median (95% CI) | 61 (59.33–62.55) | 61 (54.92–59.82) | – | 0.14 |
Ethnicity (n, %)$ | ||||
White | 103 (49.0) | 77 (46.7) | – | – |
Non-white | 106 (50.5) | 88 (53.3) | 0.9 (0.6–1.36) | 0.62 |
N/D | 1 (0.5) | 0 (0.0) | ||
Clinical follow-up (years) | ||||
Median (95% CI) | 13 (12.24–13.96) | 17 (14.29–16.57) | – | < 0.01 |
Clinical progression (n, %)$ | ||||
No | 34 (16.2) | 152 (92.2) | – | – |
Yes | 148 (70.5) | 07 (4.2) | 60.15 (29.38–123.15) | < 0.01 |
N/D | 28 (13.3) | 6 (3,6) | ||
IPEC-CDS motor subscore | ||||
Median (95% CI) | 18.65 (18.28–21.09) | 0.0 (0.48–1.34) | – | < 0.01 |
Neurogenic bladder (n, %)$ | ||||
No | 41 (19.5) | 154 (93.3) | – | – |
Yes | 167 (79.5) | 11 (6.7) | 57.02 (28.3–114.9) | < 0.01 |
N/D | 2 (1.0) | – | ||
Ophthalmic alterations (n, %) | ||||
No | 188 (89.5) | 160 (97) | – | – |
Yes | 22 (10.5) | 5 (3) | 8.98 (3.48–23.17) | < 0.01 |
Proviral load (proviral copies/cell) | ||||
Median (95% CI) | 6.49 (7.40–9.31) | 1.91 (3.16–5.18) | – | < 0.01 |
Death outcome (n, %)$ | ||||
No | 164 (78.1) | 160 (97.0) | – | – |
Yes | 24(11.4) | 0 (0) | 47.81 (2.88–793.4) | < 0.0001 |
N/D | 22 (10.5) | 5 (3.0) | – | |
