Table 5 Linear regression analysis of proviral load and HLA-A, -C and -DRB1 loci in AC Brazilian patients.

From: Putative role of HLA polymorphism among a Brazilian HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) population

Alleles

Status

β (95% CI)

P-value

β (95% CI), adjusted*

P-value*

-A*30

 Alelle absent

–

–

–

–

 Alelle present

3.128 (0.247;6.009)

0.033

2.56 (− 0.323;5.443)

0.081

-A*66

 Alelle absent

–

–

–

–

 Alelle present

4.772 (0.167;9.378)

0.042

3.826 (− 0.774;8.426)

0.103

-C*06

 Alelle absent

–

–

–

–

 Alelle present

3.912 (1.019;6.805)

0.008

3.904 (1.016;6.792)

0.008

-DRB1*15

 Alelle absent

–

–

–

–

 Alelle present

3.407 (0.773;6.041)

0.011

3.381 (0.741;6.021)

0.012

  1. AC asymptomatic carrier, 95% CI confidence interval
  2. Significant values are in bold.
  3. *p values adjusted by age, sex, ethnicity and time of clinical follow-up.
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