Figure 1

The control (n = 4) and maternal social isolation stress (MSIS (n = 4)) groups were evaluated on their distanced moved (top panel) and stereotypy time (middle panel) in activity boxes during Baseline (left) and at Lactation Day 6 (LD6) testing (right). Both groups had similar activity and exhibited a decrease in activity on LD6 compared to baseline. The amount of stereotypy time was also similar in both groups and did not change significantly between baseline and LD6. The bottom panel shows the results of the elevated plus maze test. At baseline testing, although both groups spent more time in the closed arms compared to open arms (**p < 0.01; ***p < 0.001), the control group spent significantly more time in the open arms than the MSIS group during baseline testing (*p < 0.05). There was no difference between the groups at LD6 testing in the amount of time they spent in the closed and open arms, as both groups had higher dwell times in the closed arms. Data is presented as ± SEM.