Table 2 Characteristics of participants with ALD.

From: Usefulness of health checkup for screening metabolic dysfunction-associated fatty liver disease and alcohol-related liver disease in Japanese male young adults

Characteristic

ALD (n = 3)

No ALD (n = 310)

P value

Demographics

 Age (years)

22 (± 1)

23 (± 4)

0.922

 Current/former smoking, n (%)

0 (0)

24 (8)

0.616

 Excessive alcohol intake, n (%)

3 (100)

8 (3)

< 0.001

 Exercise habits, n (%)

0 (0)

123 (40)

0.161

Physical examination

 Waist circumference (cm)

80 (± 9)

78 (± 8)

0.689

 Body mass index (kg/m2)

21.9 (± 3.8)

21.2 (± 2.9)

0.780

Comorbidity

 Diabetes, n (%)

0 (0)

0 (0)

NA

 Overweight or obesity, n (%)

1 (33)

66 (21)

0.613

Metabolic risk abnormality

 High waist circumference, n (%)

1 (33)

27 (9)

0.137

 High blood pressure, n (%)

2 (67)

74 (24)

0.085

 High TG, n (%)

1 (33)

44 (14)

0.347

 Low HDL-C, n (%)

0 (0)

13 (4)

0.717

 Prediabetes, n (%)

0 (0)

6 (2)

0.808

Laboratory test

 AST (U/L)

20 (± 4)

21 (± 13)

0.466

 ALT (U/L)

29 (± 11)

26 (± 21)

0.214

 TG (mg/dL)

110 (± 51)

99 (± 70)

0.499

 HDL-C (mg/dL)

62 (± 18)

58 (± 13)

0.453

 LDL-C (mg/dL)

95 (± 33)

97 (± 25)

0.771

 HbA1c (%)

5.1 (± 0.2)

5.2 (± 0.2)

0.506

 AUDIT

16.7 (± 4.5)

3.7 (± 4.1)

0.004

 Q1–Q3 (AUDIT-C)

8.3 (± 2.9)

2.9 (± 2.6)

0.011

 Q4–Q6

3.0 (± 1.0)

0.4 (± 0.9)

< 0.001

 Q7–Q10

5.3 (± 1.5)

0.5 (± 1.4)

< 0.001

  1. Values are presented as numbers (percentages) or means (standard deviations). Statistical differences between the two groups were analyzed using the chi-square test or Mann–Whitney U test.
  2. ALD alcohol-related liver disease; ALT alanine amino transferase; AST aspartate aminotransferase; AUDIT alcohol use disorders identification test; AUDIT-C alcohol use disorders identification test-consumption; HbA1c hemoglobin A1c; HDL-C high-density lipoprotein cholesterol; LDL-C low-density lipoprotein cholesterol; TG triglycerides.