Figure 1 | Scientific Reports

Figure 1

From: Prosaposin PS18 reduces dopaminergic neurodegeneration in a 6-hydroxydopamine rat model of Parkinson’s disease

Figure 1

PS18 antagonized 6-OHDA -mediated dopaminergic neuronal loss in rat primary ventromesencephalic culture. (A) Timeline of experiment. (B) Representing photomicrographs demonstrate that 6-OHDA reduced tyrosine hydroxylase immunoreactivity (THir), which was antagonized by PS18. (C) PS18 significantly increased THir after 6-OHDA lesioning. n = 7 per group. *p < 0.05, 1-way ANOVA + NK test.

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