Figure 4

PS18 antagonized Tg or 6-OHDA-mediated ER stress in SY5Y cell cultures. gLuc activity was quantified after treatment with (A) Tg (200 nmol/L) or (B) 6-OHDA (100 μM) (B). Tg or 6-OHDA significantly increased gLuc activity. These responses were antagonized by PS18 (A. p < 0.001; B, p < 0.001, 1-way ANOVA + NK test). (C) Timeline.