Figure 3
From: Multimodal imaging of laser-induced choroidal neovascularization in pigmented rabbits
In vivo PAM visualization of CNV lesions: (a–b) 2D PAM images achieved using different wavelengths of 578 nm (a) and 700 nm (b) at different time points: day 30, 90, and 120. Retinal vessels (RVs), nerve fibers (NFs), RPE, and formed CNV were observed with high contrast and quality using 578 nm. Note that CNV lesions were differentiated on the PAM images obtained at 700 nm at 15 min after intravenous injection of ICG dye due to the extravasation of ICG at CNV. (c) Magnification of the margin of CNV. White dotted circle indicates the boundary of CNV. Pseudo-green color shows the margin of CNV. (d) Co-registered PAM images. (e) 3D overlay images. (f) Quantification of PA signals obtained at 700 nm. (g) A graph of CNV density. Data shows as mean and standard deviation (n = 3, p < 0.005).
