Figure 6

Analysis of metabolic subtypes in the single-cell dimension. (A,B) Performance of metabolic subtype classification models on training and test datasets. (C) Quantitative distribution of the five major cell types between the two metabolic subtypes. (D) The UMAP plot of all cells, which are color-coded based on their associated clusters. (E) Differences among the three metabolic pathways enriched in cluster 1 at the bulk dimension among the five types of cells. (F–H) Differences among the 30 metabolic pathways enriched in cluster 2 at the bulk dimension among the five types of cells. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.