Table 3 The relationship between RMSSD (median) and tumour pathology, co-morbidity, systemic inflammation and survival in patients undergoing potentially curative surgery for CRC (n = 439).
RMSSD ≥ 29.8 ms | RMSSD < 29.8 ms | p value 1 | |
|---|---|---|---|
(n = 226)/ % | (n = 213) / % | ||
Age (years) | 0.7 | ||
< 65 | 104 (46%) | 85 (40%) | |
65–74 | 68 (30%) | 84 (39%) | |
> 74 | 54 (29%) | 44 (21%) | |
Sex | 0.323 | ||
Male | 121 (54%) | 104 (49%) | |
Female | 105 (46%) | 109 (51%) | |
Tumour site | 0.183 | ||
Colon | 131 (58%) | 110 (52%) | |
Rectum | 95 (42%) | 103 (48%) | |
TNM Stage | 0.267 | ||
I | 61 (27%) | 55 (26%) | |
II | 88 (39%) | 70 (33%) | |
III | 77 (34%) | 88 (41%) | |
Differentiation | 0.314 | ||
Moderate-well | 207 (92%) | 189 (89%) | |
Poor | 19 (8%) | 24 (11%) | |
Venous invasion | 0.061 | ||
No | 83 (37%) | 97 (46%) | |
Yes | 143 (63%) | 116 (54%) | |
ASA | 0.294 | ||
1 | 64 (28%) | 53 (25%) | |
2 | 111 (49%) | 104 (49%) | |
≥ 3 | 51 (23%) | 56 (26%) | |
Ischaemic heart disease | 0.219 | ||
No | 127 (56%) | 132 (62%) | |
Yes | 99 (44%) | 81 (38%) | |
Heart failure | 1 | ||
No | 223 (99%) | 210 (99%) | |
Yes | 3 (1%) | 3 (1%) | |
Diabetes mellitus | 0.172 | ||
No | 192 (85%) | 183 (86%) | |
Yes | 34 (15%) | 30 (14%) | |
AChB score | 0.048 | ||
< 3 | 198 (88%) | 172 (81%) | |
≥ 3 | 28 (12%) | 41 (19%) | |
SIG | 0.951 | ||
0 | 96 (43%) | 96 (45%) | |
1 | 68 (30%) | 52 (24%) | |
≥ 2 | 62 (27%) | 65 (31%) | |
SDNN (ms) | < 0.001 | ||
≥ 24.0 | 189 (84%) | 33 (16%) | |
< 24.0 | 37 (16%) | 180 (84%) | |
OS | 0.319 | ||
Yes | 156 (69%) | 146 (69%) | |
No | 70 (31%) | 67 (31%) | |
