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Figure 1

From: Renin-angiotensin system inhibitors mitigate radiation pneumonitis by activating ACE2-angiotensin-(1–7) axis via NF-κB/MAPK pathway

Figure 1

Analysis of histopathological changes and inflammatory factors (IL-6, TNF-α) in lung tissues by HE or immunohistochemical staining. A, Western blotting analysis (left) and quantification of ACE2 expression (right). B, HE, IL-6, and TNF-α staining. Scale bars, 10 μm. *Compared with the control group, p < 0.05. #Compared with the IR group, p < 0.05. &Compared with AAV-ACE2 group, p < 0.05. ACE2: angiotensin-converting enzyme 2; HE, hematoxylin and eosin; IR, irradiation.

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