Table 3 Association between quartiles of white blood cell count and hyper-low-density lipoprotein cholesterolemia in subgroups.
From: Elevation in white blood cell count and development of hyper LDL cholesterolemia
Quartile of white blood cell count (/μL) | P for interaction | |||||
|---|---|---|---|---|---|---|
< 4500 (N = 847) | 4500–5300 (N = 839) | 5400–6500 (N = 819) | > 6500 (N = 807) | |||
Age | ||||||
< 65 years | N of event | 83 | 121 | 110 | 121 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.50 (1.13–1.99) | 1.48 (1.10–1.98) | 1.42 (1.05–1.91) | ||
≥ 65 years | N of event | 70 | 64 | 63 | 66 | |
Hazard ratio* (95% CI) | 1 (reference) | 0.93 (0.66–1.32) | 1.06 (0.75–1.52) | 1.33 (0.94–1.90) | 0.86 | |
Gender | ||||||
Male | N of event | 40 | 80 | 85 | 105 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.33 (0.91–1.95) | 1.30 (0.89–1.89) | 1.54 (1.05–2.25) | ||
Female | N of event | 113 | 105 | 88 | 82 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.17 (0.89–1.54) | 1.29 (0.97–1.71) | 1.21 (0.89–1.64) | 0.75 | |
Smoking | ||||||
Yes | N of event | 13 | 21 | 29 | 87 | |
Hazard ratio* (95% CI) | 1 (reference) | 0.96 (0.48–1.91) | 1.01 (0.52–1.96) | 1.57 (0.87–2.82) | ||
No | N of event | 140 | 164 | 144 | 100 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.29 (1.02–1.63) | 1.36 (1.07–1.73) | 1.24 (0.95–1.62) | 0.08 | |
Exercise | ||||||
Yes | N of event | 36 | 50 | 45 | 52 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.35 (0.88–2.08) | 1.45 (0.92–2.27) | 1.90 (1.21–2.98) | ||
No | N of event | 113 | 132 | 128 | 131 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.19 (0.92–1.55) | 1.21 (0.94–1.58) | 1.19 (0.91–1.55) | 0.39 | |
Obesity | ||||||
Yes | N of event | 34 | 62 | 66 | 68 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.23 (0.81–1.88) | 1.30 (0.81–1.88) | 1.22 (0.79–1.87) | ||
No | N of event | 119 | 123 | 107 | 119 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.24 (0.96–1.61) | 1.28 (0.98–1.68) | 1.49 (1.13–1.96) | 0.77 | |
Diabetes | ||||||
Yes | N of event | 8 | 15 | 18 | 23 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.29 (0.54–3.07) | 1.30 (0.60–3.05) | 1.38 (0.61–3.12) | ||
No | N of event | 145 | 170 | 155 | 164 | |
Hazard ratio* (95% CI) | 1 (reference) | 1.21 (0.96–1.52) | 1.27 (1.00–1.60) | 1.34 (1.05–1.70) | 0.98 | |
