Figure 1 | Scientific Reports

Figure 1

From: The QuantuMDx Q-POC SARS-CoV-2 RT-PCR assay for rapid detection of COVID-19 at point-of-care: preliminary evaluation of a novel technology

Figure 1The alternative text for this image may have been generated using AI.

QuantuMDx Q-POC and Q-CAS, point-of-care diagnostic for detection of SARS-CoV-2 from mid-nasal (MN) swab samples. (A) Graphic showing the Q-POC/Q-CAS workflow. A MN swab is collected and resuspended in Copan MSwab (3 ml). The tube is inverted 5 times before 400 µl is dispensed into the inlet of the cassette using a pipette. The barcode is scanned, Q-POC identifies the cassette, the cassette is inserted and Q-POC begins the SARS-CoV-2 assay. A result is displayed on screen in ~ 30 min. (B) Key areas of the Q-CAS cassette. Q-POC interacts with the self-contained cassette to move the sample from the inlet through the lyophilised reagents and into the shuttle flow PCR region. RT-PCR amplification is detected during shuttling through the detection region. (C) Results graph for a positive SARS-CoV-2 sample. The assay results in PCR curves for SARS-CoV-2 (in red) and sample control, RNase P (in yellow). This screen is optionally displayed after the main results screen whereby a definitive result is displayed (positive/negative/invalid). Results can be reviewed, printed and uploaded.

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