Table 2 Glucose and lipid metabolism in young normal weight Japanese women according to homeostasis model assessment-insulin resistance values: insulin sensitive (IS), borderline and insulin resistant (IR) groups.

From: Association between serum leptin concentrations and homeostasis model assessment-insulin resistance of 2.5 and higher in normal weight Japanese women

 

IS

Borderline

IR

*

Fasting glucose (mg/dL)

81 ± 6

86 ± 6

89 ± 9

a,b

2-h glucose (mg/dL)#

92 ± 24

92 ± 14

117 ± 20

 

Fasting insulin (μU/mL)

5 ± 2

9 ± 2

14 ± 4

a,b,c

2-h insulin (μU/mL)#

37 ± 24

49 ± 11

98 ± 25

b,c

HbA1c (%)

5.2 ± 0.2

5.2 ± 0.3

5.2 ± 0.3

 

HOMA-β

103 ± 67

162 ± 65

257 ± 248

a,b,c

HOMA-IR

0.9 ± 0.4

2.0 ± 0.3

3.1 ± 0.9

a,b,c

AUCg (mg/dL/2 h)#

204 ± 43

199 ± 37

251 ± 56

 

AUCi (μU/mL/2 h)#

73 ± 32

130 ± 54

146 ± 22

a,b

Triglycerides (mg/dL)

53 ± 21

67 ± 37

68 ± 29

a,b

Cholesterol (mg/dL)

182 ± 26

184 ± 29

188 ± 25

 

HDL-C (mg/dL)

75 ± 13

73 ± 16

77 ± 9

 

RLP-C (mg/dL)

2.7 ± 0.9

3.0 ± 1.2

3.6 ± 1.7

b

FFA (mEq/L)

0.53 ± 0.21

0.61 ± 0.23

0.73 ± 0.34

b

  1. Mean ± SD, #: n = 89, 7 and 3 in IS, borderline and IR, respectively, HOMA-IR and HOMA-β: homeostasis model assessment-insulin resistance and secretion, respectively, AUCg and AUCi: area under the response curve of glucose and insulin, respectively, HDL-C: high-density lipoprotein cholesterol, RLP-C: remnant-like particle cholesterol, FFA: free fatty acid. *: the same as in Table 1.