Figure 2 | Scientific Reports

Figure 2

From: LncRNA FAS-AS1 upregulated by its genetic variation rs6586163 promotes cell apoptosis in nasopharyngeal carcinoma through regulating mitochondria function and Fas splicing

Figure 2The alternative text for this image may have been generated using AI.

FAS-AS1 was downregulated in NPC and correlated with prognosis of various cancers. (a) The gene expression profile of FAS-AS1 across all tumor samples and paired normal tissues. Each dots represent expression of samples. (b) Relative expression of FAS-AS1 in NPC tissues and rhinitis tissues were examined by RT-qPCR. (c) The expression level of FAS-AS1 was associated with clinical stage of NPC patients. (d) The expression level of FAS-AS1 was associated with short-term treatment efficacy of NPC patients. (e) Relative expression of FAS in NPC tissues and rhinitis tissues were examined by RT-qPCR. (f) The expression level of FAS was associated with clinical stage of NPC patients. (g) The expression level of FAS was not associated with short-term treatment efficacy of NPC patients. (h) Correlation analysis of FAS-AS1 and FAS in NPC tissues. (i–l) FAS-AS1 was associated with survival in breast cancer (i), ovarian cancer (j), lung cancer (k), and gastric cancer (l). *P < 0.05, **P < 0.01.

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