Table 1 Demographic information of responders and non-responders from proprietary dataset and the TD-BRAIN dataset. aAD (Antidepressant), MS (mood stabilizer), AP (antipsychotic). bMedication type is not specified.
Proprietary dataset | TD-BRAIN dataset | |||||
|---|---|---|---|---|---|---|
Non-responders | Responders | p-value | Non-responders | Responders | p-value | |
N | 23 | 23 | 45 | 79 | ||
Age | 39 (± 14.6) | 30.9 (± 12.3) | 0.052 | 46.7 (± 13.9) | 41.0 (± 12.2) | 0.038 |
Gender (M/F) | 8/15 | 8/15 | 0.9 | 26/19 | 38/41 | 0.30 |
Pre-treatment BDI-II | 28.1 (± 9.4) | 32.5 (± 9.3) | 0.08 | 33.1 (± 11.4) | 29.9 (± 8.9) | 0.06 |
Post-treatment BDI-II | 23.1 (8.4) | 8.6 (± 5.9) | < 0.001 | 28.3 (10.8) | 7.1 (± 5.5) | 0.01 |
Illness duration (years) | 7.9 (± 7.8) | 6.5 (± 8.2) | 0.278 | – | – | – |
Number of previous medications | 2.7 (± 1.5) | 2 (± 2.1) | 0.108 | – | – | – |
Medications (AD/AD + MS / AD + MS + AP)a | 5/8/1 | 6/6/0 | X2 = 0.2, p = 0.65 | 15b | 36b | – |
Anxiety (Y/N) | 14/9 | 19/4 | p = 0.052 | – | – | – |
