Figure 6 | Scientific Reports

Figure 6

From: Association analysis of gut microbiota-metabolites-neuroendocrine changes in male rats acute exposure to simulated altitude of 5500 m

Figure 6

Causal mediation analysis revealed potential fecal and serum metabolites mediating the causal relationship between hormones with gut microbes. Blue lines, negatively coefficient; Red lines, positively coefficient. The arrows drown from metabolites to bacterial genus and hormones, and from bacterial genus and hormones to metabolites imply the conception that those indicators affect one another in the direction depicted. CORT corticosterone, TRH thyrotropin-releasing hormone, tT4 thyroxine.

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