Table 3 Comparison of HRCT findings between pSS patients with and without ILD progression.

Baseline CT findings

 UIP pattern, n (%)

7 (17.9)

6 (31.6)

1 (5.0)

0.044^a

 OP pattern, n (%)

3 (7.7)

0 (0.0)

3 (15.0)

0.231^a

 Total disease extent

23.0 (15.5, 34.0)

23.0 (15, 36)

23.0 (15.5, 31.0)

1.000^b

 Extent of GGO

5.4 (3.1, 8.1)

5.1 (2.8,7.9)

6.4 (3.9, 8.5)

0.391^b

 Extent of fine reticulation

8.9 (6.3, 12.4)

8.0 (6.2, 11.9)

9.1 (7.4, 12.3)

0.708^b

 Extent of coarse reticulation

5.34 (0.1, 19.0)

8.3 (1.1–71.5)

1.7 (0.2, 1.59)

0.385^b

 Presence of HC, n (%)

18 (46.1)

11 (57.9)

7 (35.0)

0.248^a

 Coarseness score of fibrosis (0–15)

5 (4, 8)

5 (4, 10)

5 (3.7–7.2)

0.343^b

 Scores of traction bronchiectasis (0–15)

7 (3, 9.5)

7 (3, 11)

6.5 (2.7–9.0)

0.391^b

Last follow-up CT findings

 Total disease extent

28.0 (19.0, 40.5)

30 (23.0, 46.0)

22.5 (14.0, 32.5)

0.036^b

 Extent of GGO

3.8 (1.5, 6.4)

3.01 (1.5, 5.2)

5.13 (2.2, 7.0)

0.327^b

 Extent of fine reticulation

9.3 (7.34, 12.9)

9.24 (8.3, 12.9)

9.52 (4.4, 12.8)

0.418^b

 Extent of coarse reticulation

11.7 (1.8, 26.6)

19.8 (5.7, 31.2)

4.8 (0.28, 23.8)

0.025^b

 Presence of HC, n (%)

27 (69.2)

15 (78.9)

12 (60.0)

0.476^a

 Coarseness score of fibrosis (0–15)

7 (5, 10.5)

9 (5, 13)

6.5 (3.75, 9.0)

0.031^b

 Scores of traction bronchiectasis (0–15)

8 (5, 12)

11 (6, 13)

6.5 (3.7, 10.0)

0.066^b

Absolute changes of HRCT scores between baseline and last follow-up

 Total disease extent

3 (0–9)

9 (4–12)

0 (0–2.0)

 < 0.001^b

 Extent of GGO

-1.2 (-3.4, -0.2)

-1.3 (-4.1,-0.0)

-1.1 (-3.4,-0.5)

0.893^b

 Extent of fine reticulation

0.3 (-1.1, 1.6)

0.4 (-0.1, 3.5)

0.2 (-0.8, 0.9)

0.425^b

 Extent of coarse reticulation

3.7 (0.6–11.2)

9.12 (3.6, 15.1)

1.25 (0, 4.2)

0.003^b

 Coarseness score of fibrosis (0–15)

2 (0, 3)

2 (1, 4)

1 (0, 2)

0.189^b

 Scores of traction bronchiectasis (0–15)

0 (1, 3)

3 (1, 3)

0.5 (0, 2)

0.011^b

Annual changes of HRCT scores

△Total disease extent/year

0.7 (0, 2.6)

2.4 (0.5, 3.7)

0.0 (0.0, 0.7)

0.001^b

△Extent of GGO/year

-0.4 (-0.9, -0.5)

-0.2 (-0.7, -0.0)

-0.5 (-1.1, -0.2)

0.118^b

△Extent of fine reticulation/year

0.0 (-0.6, 3.5)

0.0 (-0.4, 0.6)

0.0 (-0.9, 0.4)

0.708^b

△Extent of coarse reticulation/year

0.4 (0.0, 0.7)

1.6 (0.6, 3.9)

0.5 (0.0, 2.0)

0.021^b

△Coarseness score of fibrosis/year

0.4 (0.0, 0.7)

0.5 (0.1, 0.7)

0.3 (0.0, 0.6)

0.461^b

△Scores of traction bronchiectasis/year

0.3 (0.0, 0.7)

0.5 (0.1, 0.7)

0.1 (0.0, 0.7)

0.223^b