Figure 2
The effect of Lavandula coronopifolia essential oil on AMPA receptor homomeric and heteromeric subunits' currents. Figure (a) shows the whole-cell recordings of amplitudes (pA) obtained from HEK293T-expressing AMPAR-type subunits (i.e., GluA1, GluA1/A2, GluA2, and GluA2/A3), conducted at − 60 mV, pH 7.4, and 22 °C after treating the cell with 10 mM glutamate (blue) alone, and Glu with a fixed concentration of 120 μM of Lavandula coronopifolia oil (red) for 500 ms. Lavandula coronopifolia oil concentration was chosen for its highest effect without affecting the health of the cells. Figures (b, c, d,) and e show the A/AI ratio, where A represents the current generated by glutamate alone, and AI represents the current caused by glutamate + Lavandula coronopifolia oil. Data shown are mean ± SEM; n = 8 (number of patch cells in the whole-cell configuration). Significance was calculated using one-way ANOVA, ns, not significant.
