Table 4 Effect of manganese (Mn) and manganese nanoparticles (Mn-NPs) on lipid peroxidation (LPO), acetyl choline esterase (AChE), glucose-6-phosphate dehydrogenase (G6PDH) and ATPase in Pangasianodon hypophthalmus for a period of 96 h.

From: Multi biomarker approach to assess manganese and manganese nanoparticles toxicity in Pangasianodon hypophthalmus

Manganese exposure (mg/L)

Lipid peroxidation (LPO)

Acetyl choline esterase (AChE)

Glucose-6-phosphate dehydrogenase (G6PDH)

ATPase

Liver

Gill

Kidney

Brain

Liver

Gill

Liver

Gill

Control (Mn-0, Mn-NPs-0)

6.65a ± 0.53

2.95a ± 0.51

8.84a ± 2.32

0.63e ± 0.01

0.22a ± 0.02

0.27a ± 0.04

109.83a ± 10.37

68.69a ± 8.45

Mn-110

13.00b ± 0.47

8.03b ± 0.59

16.14c ± 1.17

0.43d ± 0.01

0.33b ± 0.05

0.38c ± 0.05

148.79e ± 11.14

91.24c ± 13.35

Mn-111

14.29b ± 0.35

10.54bc ± 0.87

16.63c ± 1.52

0.40d ± 0.03

0.33b ± 0.05

0.39c ± 0.04

150.49e ± 11.63

98.15d ± 9.14

Mn-112

18.85c ± 1.16

12.77c ± 1.0

17.84c ± 1.16

0.39d ± 0.02

0.33b ± 0.01

0.40c ± 0.03

118.97b ± 8.19

106.15e ± 7.94

Mn-113

20.77cd ± 0.48

18.58d ± 0.91

22.51de ± 0.66

0.32b ± 0.01

0.39bc ± 0.03

0.47d ± 0.02

171.96f ± 9.13

95.29cd ± 9.43

Mn-114

24.62d ± 1.13

20.78e ± 1.09

29.85e ± 1.39

0.31ab ± 0.04

0.47c ± 0.05

0.48d ± 0.01

184.67g ± 11.54

143.01h ± 15.38

Mn-NPs-91

11.78b ± 0.73

9.46bc ± 1.07

11.14b ± 1.19

0.41d ± 0.05

0.30b ± 0.03

0.33b ± 0.02

128.53c ± 10.43

78.53b ± 12.61

Mn-NPs-92

12.56b ± 1.10

10.25bc ± 1.16

12.84b ± 0.91

0.42d ± 0.02

0.32b ± 0.07

0.39c ± 0.03

144.53d ± 12.66

97.23d ± 7.39

Mn-NPs-93

13.43bc ± 1.21

12.77c ± 0.67

14.14bc ± 0.54

0.36c ± 0.03

0.37bc ± 0.02

0.43 cd ± 0.04

131.99c ± 8.66

114.19f ± 7.78

Mn-NPs-94

17.80c ± 0.52

18.71d ± 0.44

13.51bc ± 0.32

0.33b ± 0.02

0.44c ± 0.04

0.47d ± 0.08

156.28f ± 9.01

132.13g ± 11.25

Mn-NPs-95

18.29c ± 0.90

19.07de ± 0.92

20.91d ± 1.32

0.27a ± 0.01

0.43c ± 0.03

0.42cd ± 0.06

141.26d ± 10.49

151.52i ± 8.03

p-value

< 0.01

< 0.01

< 0.01

< 0.01

< 0.01

< 0.01

< 0.01

< 0.01

  1. Values in the same column with different (a, b, c, d, e, f, g) differ significantly (p < 0.01). Data expressed as mean ± SE (n = 6). LPO: n mole TBARS formed/h/mg protein, Acetyl choline esterase (AChE): nmole/min/mg protein, G6PDH: Change in 0.01 OD/min/mg protein; ATPase: µg phosphorus released/min/mg protein.
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