Table 2 Protein biomarkers associated with progression of SSc–ILD.
Protein name | UniProt database identifier | Z score | Association with progression | p value |
|---|---|---|---|---|
DBNL | Q9UJU6 | 2.85 | Positive | 0.004 |
Uncharacterized protein Fragment 2 | A0A0J9YY99 | 2.38 | Positive | 0.018 |
RIN3 | Q8TB24 | 2.22 | Positive | 0.027 |
PDCD6 | O75340 | 2.17 | Positive | 0.030 |
RNASE3 | P12724 | 2.14 | Positive | 0.032 |
KRT2 | P35908 | 2.14 | Positive | 0.032 |
IGHV3-49 | A0A0A0MS15 | 2.13 | Positive | 0.033 |
Uncharacterized protein Fragment 1 | A0A0J9YY99 | 2.06 | Positive | 0.040 |
KRT9 | P35527 | 2.05 | Positive | 0.041 |
LYZ | P61626 | 2.04 | Positive | 0.042 |
IGKJ3 | A0A0A0MT96 | 2.03 | Positive | 0.043 |
LILRA3 | Q8N6C8 | 3.29 | Positive | 0.044 |
PRTN3 | P24158 | 1.99 | Positive | 0.047 |
CDH2 | P19022 | − 2.63 | Negative | 0.008 |
NEO1 | Q92859 | − 2.57 | Negative | 0.010 |
A1BG | P04217 | − 2.43 | Negative | 0.015 |
B3GNT2 | Q9NY97 | − 2.39 | Negative | 0.017 |
ZNF500 | ZNF500 | − 2.27 | Negative | 0.023 |
SERPINF2 | P08697 | − 2.25 | Negative | 0.024 |
BTD | P43251 | − 2.23 | Negative | 0.026 |
KLKB1 | P03952 | − 2.19 | Negative | 0.028 |
PLG | P00747 | − 2.18 | Negative | 0.029 |
ANPEP | P15144 | − 2.11 | Negative | 0.035 |
YBX2 | Q9Y2T7 | − 2.11 | Negative | 0.035 |
PON1 | P27169 | − 2.11 | Negative | 0.036 |
HLA− H | P01893 | − 2.09 | Negative | 0.037 |
FETUB | Q9UGM5 | − 2.04 | Negative | 0.041 |
BCHE | P06276 | − 2.02 | Negative | 0.044 |
ENG | P17813 | − 1.99 | Negative | 0.047 |
