Table 2 Preparation of various propargyl amines under optimum conditions.

From: Gold nanoparticle decorated post-synthesis modified UiO-66-NH2 for A3-coupling preparation of propargyl amines

View full size image

Entry

Aldehyde

Amine

Product

Time (h)

Yield (%)

1

2.5

95

2

2.5

97

3

2.5

91

4

2.5

90

5

2.5

93

6

2.5

95

7

2.5

92

8

2.5

91

9

2.5

92

10

2.5

94

11

2.5

90

12

2.5

95

13

2.5

93

14

2.5

92

15

2.5

94

16

2.5

93

17

2.5

95

18

2.5

97

19

2.5

98

20

2.5

79

  1. Reaction conditions: 1 mmol of morpholine, 1 mmol of benzaldehyde, and 1.1 mmol of phenylacetylene.
Back to article page