Table 1 Participant characteristics.
MDD (n = 48) | Non-responders (n = 22) | Responders (n = 10) | NR versus R p value | |
|---|---|---|---|---|
Sociodemographic characteristics | ||||
Age, years | 34.9 (10.7) | 37.1 (11.7) | 35.8 (8.78) | 0.732 |
Sex, female n (%) | 26 (54.2%) | 11 (50.0%) | 6 (60.0%) | χ2 = 0.020 p = 0.886 |
Race/ethnicity, n (%) | ||||
White | 22 (45.8%) | 13 (59.1%) | 5 (50.0%) | χ2 = 2.004 p = 0.735 |
Black | 4(8.3%) | 1 (4.55%) | 1 (10.0%) | |
Asian | 12(25%) | 5 (22.7%) | 1 (10.0%) | |
More than one | 6(12.5%) | 2 (9.09%) | 2 (20.0%) | |
Other | 4(8.3%) | 1 (4.55%) | 1 (10.0%) | |
Years of education (n = 47) | 16.0 (2.3) n = 47 | 15.8 (2.43) | 16.3 (2.67) | 0.602 |
Lifestyle factors | ||||
Body mass index | 25.2 (4.1) | 25.3 (4.07) | 24.7 (5.02) | 0.778 |
Smoking status, n (%) | ||||
Never | 31 (64.6%) | 15 (68.1%) | 4 (40%) | χ2 = 3.0275 p = 0.220 |
Former | 13 (27.1%) | 6 (27.3%) | 4 (40%) | |
Current | 4 (8.3%) | 1 (4.6%) | 2 (20%) | |
HgbA1c | 5.3 (0.38) | 5.30 (0.35) | 5.12 (0.48) | 0.307 |
MAP | 86.6 (9.8) | 88.8 (10.1) | 83.6 (7.80) | 0.125 |
Triglyceride (TyG) index (n = 45) | 4.44 (0.29) | 4.43 (0.31) | 4.44 (0.39) | 0.967 |
Cardiometabolic Risk (CR) score | 4.05 (0.11) | 4.07 (0.10) | 4.01 (0.13) | 0.275 |
Allostatic Load Score (n = 45) | 3 (1.71) | 3.20 (1.67) | 2.70 (2.16) | 0.531 |
Symptoms | ||||
Hamilton Depression Rating Scale (HDRS) | 19.4 (3.4) | 19.4 (2.89) | 18.3 (3.62) | 0.408 |
Perceived stress scale (PSS) (n = 45) | 26.0 (5.7) | 25.2 (5.63) | 26.7 (6.41) | 0.529 |
Duration of depression (months) (n = 42) | 190.6 (162) | 226 (172) | 152 (143) | 0.329 |
Telomere/telomerase variables | ||||
T/S ratio | 0.96 (0.18) | 0.89 (0.16) | 1.04 (0.10) | 0.005 |
Telomerase activity (n = 47) | 11.5 (12.4) | 14.4 (16.7) | 7.36 (4.09) | 0.375 |
