Table 4 Relationships between telomere length or telomerase and cardiometabolic indices.

From: Shorter telomere length predicts poor antidepressant response and poorer cardiometabolic indices in major depression

 

Telomere length

Telomerase

b (95% CI)

β

p value

b (95% CI)

β

p value

TyG Index

 Model 1

− 0.105 (− 0.288, 0.077)

− 0.171

0.25

0.147 (− 0.204, 0.498)

0.125

0.404

 Model 2

− 0.086 (− 0.254, 0.082)

− 0.14

0.308

0.181 (− 0.149, 0.511)

0.154

0.274

 Model 3

− 0.128 (− 0.314, 0.058)

− 0.208

0.17

0.170 (− 0.198, 0.538)

0.144

0.355

CR score

 Model 1

− 0.511 (− 0.978, − 0.043)

− 0.309

0.033

0.391 (− 0.532, 1.31)

0.125

0.398

 Model 2

− 0.497 (− 0.928, − 0.066)

− 0.3

0.025

0.416 (− 0.452, 1.28)

0.133

0.34

 Model 3

− 0.445 (− 0.909, 0.019)

− 0.269

0.06

0.389 (− 0.544, 1.32)

0.124

0.405

  1. Model 1. Unadjusted.
  2. Model 2. Adjusted for age.
  3. Model 3. Further adjusted for Gender, Race, and Smoking status.
  4. CR score = Cardiometabolic Risk score; TyG index = Triglyceride index.
  5. n = 47 for correlation between with TyG index due to exclusion.
  6. *Bonferroni-corrected p value for significance was p = 0.025 (0.05/2).
  7. Significant values are in bold.
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