Figure 3 | Scientific Reports

Figure 3

From: Reduced vmPFC-insula functional connectivity in generalized anxiety disorder: a Bayesian confirmation study

Figure 3

Differences in resting-state FC between GAD and HC revealed by the frequentist analysis. (A) The solid line indicates a significantly decreased FC between the PMI and vmPFC in GAD participants after multiple comparison correction using the Bonferroni method. Dotted lines indicate differences in FC between the PMI and amygdala, AI and vmPFC, and dlPFC and amygdala that did not remain statistically significant after Bonferroni correction. Each brain region, indicated by different colors, reflects the selected labels drawn from the Brainnetome atlas. (B) Raincloud plots of Fisher r-to-z transformed correlation coefficients between the PMI and the vmPFC BOLD-signal time series. FC functional connectivity, GAD generalized anxiety disorder, HC healthy comparison, vmPFC ventromedial prefrontal cortex, PMI posterior-mid insula, AI anterior insula, dlPFC dorsolateral prefrontal cortex.

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