Table 2 Demographic and clinical characteristics of study sample.

From: Reduced vmPFC-insula functional connectivity in generalized anxiety disorder: a Bayesian confirmation study

 

GAD

n = 27 females

HC

n = 28 females

∆M

95% CI

df

t

p

Age (years)

26.2 ± 6.5

24.2 ± 5.1

− 1.99

[− 5.12, 1.18]

49.23

− 1.26

0.214

BMI (kg/m2)

25.9 ± 4.7

24 ± 3.2

− 1.86

[− 4.04, 0.32]

45.5

− 1.72

0.092

PHQ-9

11.5 ± 5

0.7 ± 1.1

− 10.8

[− 12.82, − 8.78]

28.37

− 10.96

 < 0.001

OASIS

11 ± 2.2

1.1 ± 1.6

− 9.82

[− 10.87, − 8.78]

46.97

− 18.9

 < 0.001

GAD-7

13.7 ± 3.4

1 ± 1.5

− 12.74

[− 14.19, − 11.29]

35.93

− 17.78

 < 0.001

STAI-State

44.1 ± 9.3

24.7 ± 5.6

− 19.37

[− 23.59, − 15.15]

42.48

− 9.26

 < 0.001

STAI-Trait

58 ± 6.7

28.2 ± 6.9

− 29.81

[− 33.51, − 26.12]

51.93

− 16.17

 < 0.001

ASI-Total

28 ± 14.6

7.2 ± 4

− 20.71

[− 26.67, − 14.76]

29.74

− 7.1

 < 0.001

  1. All values presented as means ± standard deviation. Differences between group means (∆M) and corresponding 95% uncertainty intervals (CI) are reported. Welch’s independent samples t-tests were conducted to assess differences between the groups. Data for the STAI was missing from one HC participant. GAD generalized anxiety disorder, HC healthy comparison, df degrees of freedom, BMI body mass index, PHQ-9 Patient Health Questionnaire-9, OASIS Overall Anxiety Severity and Impairment Scale, GAD-7 7-item generalized anxiety scale, STAI State-Trait Anxiety Inventory, ASI Anxiety Sensitivity Index.