Figure 10 | Scientific Reports

Figure 10

From: Latent toxoplasmosis impairs learning and memory yet strengthens short-term and long-term hippocampal synaptic plasticity at perforant pathway-dentate gyrus, and Schaffer collatterals-CA1 synapses

Figure 10

Enhanced LTP of PS and fEPSP slope at Schaffer collaterals to CA1 synapses in T. gondii-infected rats. (A) Representative traces of evoked field potentials in the CA1 recorded before and after HFS. The orange line shows the potentiated fEPSP at 30 min post-HFS period. (B) Time course of the PS-LTP in the experimental groups (n = 8 for each group). (C) Comparison of the mean post-HFS population spikes in un-infected and T. gondii-infected rats during 90 min recording period. (D) Time course of the fEPSP slope-LTP in the experimental groups. (E) Comparison of the mean post-HFS fEPSP slope in un-infected and T. gondii-infected rats during whole 90 min recording period (n = 7 for each group). Data are presented as mean ± SEM. ***P < 0.001.

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