Table 1 Identified genes by two approaches (FST and log2 θπ ratio) controlling immune responses and hot stress traits in West and South Asian indigenous ecotypes.
Statistical-method | Gene | Chromosome | Summary of gene function |
|---|---|---|---|
FST (top 1%)-pi (top 1%) | RYR1 | 18 | Immune response48 |
LRFN5 | 21 | ||
FST (top 1%) | CDH9 | 20 | Environmental adaptation15 |
MSRB3 | 5 | Heat stress48 | |
HERC6 | 6 | Environmental adaptation15 | |
pi (top 1%) | NBEA | 12 | Heat stress15 |
HSPB6 | 18 | Heat stress29 | |
HSF4 | 1 | Heat stress30 | |
MYO1A | 5 | Heat stress49 | |
RAD50 | 7 | Environmental adaptation19 | |
SHQ1 | 22 | ||
VPS13A | 8 | ||
KITLG | 5 | Environmental adaptation50 | |
PGLYRP1 | 18 | Immune response51 | |
IL7 | 14 | Immune response47 | |
IL5 | 7 | Immune response18 | |
IFNAR2 | 1 | Immune response20 | |
PTAFR | 2 | Immune response28 | |
RC3H1 | 16 | Immune response21 | |
STAT2 | 5 | Immune response52 | |
IL23A | 5 | Resistance to gastrointestinal parasite9 | |
NOS2 | 19 | Resistance to haemonchus contortus in sheep and goats53 |