Table 2 Diagnostic performance of CD117+CD105+NEC (% of CD105+NEC), CD36 CV, and CD36 RMFI to differentiate between MDS and MA.

From: CD36 relative mean fluorescence intensity of CD105+ nucleated erythroid cells can be used to differentiate myelodysplastic syndrome from megaloblastic anemia

 

CD36 RMFI

CD117+CD105+NEC (%)

CD36 CV

Area under the curve

0.844

0.638

0.685

95% CI lower

0.753

0.509

0.559

95% CI upper

0.935

0.767

0.810

Cut-off value

474.36

17.59

83.11

Sensitivity

94.3%

64.9%

37.8%

Specificity

67.6%

65.7%

100.0%

Accuracy

80.6%

65.3%

72.2%

Positive predictive value

73.3%

66.7%

70.7%

Negative predictive value

92.6%

63.9%

74.2%

  1. CI confidence interval, CV coefficient of variation, RMFI relative mean fluorescence intensity, MDS myelodysplastic syndrome, MA megaloblastic anemia, NEC nucleated erythroid cells.