Table 2 Renal biological data.

From: Pulmonary hypertension without heart failure causes cardiorenal syndrome in a porcine model

 

PH (n = 6)

SHAM (n = 6)

p-value

Blood analysis

Sodium (mmol/L)

139.1 ± 2.6

138.6 ± 2.1

0.70

Potassium (mmol/L)

3.5 ± 0.2

3.8 ± 0.2

0.11

Chloride (mmol/L)

99.5 ± 3.5

99.8 ± 1.3

0.94

Bicarbonate (mmol/L)

28.9 ± 3.4

28.9 ± 1.7

0.98

Calcium (mmol/L)

2.28 ± 0.1

2.37 ± 0.12

0.17

Phosphorus (mmol/L)

2.74 ± 0.29

2.51 ± 0.11

0.10

Plasma urea (mmol/L)

3.3 ± 1.9

3.2 ± 0.8

0.88

Serum creatinine (SCr) (µmol/L)

99 ± 8.3

97.8 ± 5

0.82

SCr to weight ratio (µmol/L/kg)

3.26 ± 0.78

2.94 ± 0.23

0.36

SCr to BSA ratio (µmol/L/cm2)

1.43 ± 0.25

1.34 ± 0.11

0.40

eGFR (mL/min/kg)

5.16 ± 1.02

5.52 ± 0.34

0.43

Total protein (g/L)

45.3 ± 3.3

45.1 ± 3

0.89

Urine analysis

Natriuresis (mmol/L)

65 ± 31

62 ± 30

0.90

Kaliuresis (mmol/L)

78 ± 33

90 ± 28

0.52

Chloruresis (mmol/L)

44 ± 39

64 ± 29

0.32

Urine creatinine (mmol/L)

14.6 ± 5.3

11 ± 3.5

0.20

Urine urea (mmol/L)

100 ± 91

97 ± 43

0.94

Fractional excretion of urea (FEUrea) (%)

18.2 ± 6.2

26.8 ± 6.2

0.04

Fractional excretion of sodium (FeNa) (%)

3.4 ± 1.6

4.7 ± 3.1

0.40

Albuminuria (mg/L)

4.4 ± 0.6

2.9 ± 0.4

 < 0.001

Urine albumin to creatinine ratio (UACR) (mg/mmol)

0.45 ± 0.22

0.27 ± 0.08

0.09

  1. Characterization of renal injury by blood and urine sample, at the time of sacrifice.
  2. BSA: body surface area; eGFR: estimated glomerular filtration rate; FeNa: fractional excretion of sodium; FeUrea: fractional excretion of urea; PH: pulmonary hypertension; SCr: serum creatinine; UACR: urine albumin to creatinine ratio.