Table 1 Comparison of study populations.
Control (n = 3,268,693) | Cerebral palsy (n = 10,223) | P-value | |
|---|---|---|---|
Maternal age (years) | 30.876 ± 3.87 | 30.9997 ± 4.07 | 0.002 |
Maternal age > 35 years | 538,542 (16.48%) | 1871 (18.3%) | < 0.001 |
Hypertension | 106,401 (3.26%) | 500 (4.89%) | < 0.001 |
DM | 156,421 (4.79%) | 647 (6.33%) | < 0.001 |
Cesarean delivery | 1,178,746 (36.06%) | 4873 (47.67%) | < 0.001 |
Gestational hypertension | 62,801 (1.92%) | 643 (6.29%) | < 0.001 |
GDM without insulin | 276,871 (8.47%) | 834 (8.16%) | 0.258 |
GDM with insulin | 25,193 (0.77%) | 165 (1.61%) | < 0.001 |
Chorioamnionitis | 23,195 (0.71%) | 266 (2.6%) | < 0.001 |
Premature rupture of membrane | 518,472 (15.86%) | 2327 (22.76%) | < 0.001 |
Oligohydramnios | 34,660 (1.06%) | 356 (3.48%) | < 0.001 |
Polyhydramnios | 3394 (0.1%) | 88 (0.86%) | < 0.001 |
Preterm birth (< 37 weeks) | < 0.001 | ||
< 28 weeks | 12,452 (0.38%) | 838 (8.20%) | |
28–33/6 weeks | 22,400 (0.69%) | 1457 (14.25%) | |
36/6 weeks | 57,472 (1.76%) | 631 (6.17%) | |
Term birth (≥ 37 weeks) | 3,176,369 (97.18%) | 7297 (71.38%) | < 0.001 |
With BW < 2500 g | 62,148 (1.9%) | 747 (7.31%) | |
With 2.5 kg ≤ BW < 4.0 kg | 2,990,361 (91.48%) | 6307 (61.69%) | |
With BW ≥ 4.0 kg | 123,860 (3.79%) | 243 (2.38%) | |
Male | 1,683,526 (51.5%) | 5984 (58.53%) | < 0.001 |
Respiratory distress syndrome | 6681(0.2%) | 140(1.37%) | < 0.001 |
Bronchopulmonary dysplasia | 76(0%) | 2(0.02%) | 0.0004 |
Necrotizing enterocolitis | 148(0%) | 5(0.05%) | < 0.001 |
