Table 2 Risk factors for developing cerebral palsy in singleton pregnancy.

From: Declining incidence of cerebral palsy in South Korea

 

Unadjusted OR (95% CI)

Adjusted OR (95% CI)

Maternal age > 35 years

1.14 (1.08–1.19)

0.99 (0.94–1.04)

HTN

1.53 (1.40–1.67)

1.11 (1.01–1.22)

DM

1.35 (1.24–1.46)

1.15 (1.06–1.25)

Cesarean delivery

1.62 (1.55–1.68)

1.33 (1.27–1.38)

Preeclampsia

3.43 (3.16–3.71)

1.18 (1.08–1.28)

GDM without insulin

0.96 (0.90–1.03)

0.83 (0.77–0.90)

GDM with insulin

2.12 (1.81–2.47)

1.47 (1.23–1.75)

Chorioamnionitis

3.74 (3.31–4.23)

1.54 (1.36–1.75)

Preterm rupture of membrane

1.56 (1.49–1.64)

1.13 (1.07–1.18)

Oligohydramnios

3.37 (3.03–3.74)

1.67 (1.50–1.87)

Polyhydramnios

8.37 (6.77–10.35)

3.81 (3.04–4.77)

Preterm birth

< 28 weeks

31.91 (29.63–34.37)

29.49 (27.35–31.79)

28–33/6 weeks

30.84 (29.09–32.70)

24.55 (23.00–26.20)

34–36/6 weeks

5.21 (4.80–5.65)

4.54 (4.18–4.94)

Term birth with BW < 2500 g

5.70 (5.28–6.15)

5.39 (4.99–5.82)

With 2.5 kg ≤ BW < 4.0 kg

1

1

With BW ≥ 4.0 kg

0.93 (0.82–1.06)

0.86 (0.76–0.98)

Male

1.33 (1.28–1.38)

1.32 (1.27–1.38)

Respiratory distress syndrome

6.78 (5.73–8.03)

2.04 (1.69–2.47)

Bronchopulmonary dysplasia

8.58 (2.13–34.49)

1.27 (0.31–5.24)

Necrotizing enterocolitis

10.81 (4.43–26.36)

2.80 (1.14–6.87)

  1. Multivariate logistic regression analysis was used to estimate the adjusted odds ratio (OR) and 95% confidence interval (CI). BW, body weight. Adjusted for variables in the table.